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	<title>BHD Research</title>
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	<description>Your Resource for Birt-Hogg-Dubé Syndrome</description>
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		<title>Wellcome Trust Monitor – Public opinion about medical research</title>
		<link>http://bhdresearch.scienceblog.com/487/wellcome-trust-monitor-public-opinion-about-medical-research/</link>
		<comments>http://bhdresearch.scienceblog.com/487/wellcome-trust-monitor-public-opinion-about-medical-research/#comments</comments>
		<pubDate>Fri, 14 Jun 2013 07:00:30 +0000</pubDate>
		<dc:creator>bhdresearch</dc:creator>
				<category><![CDATA[Uncategorized]]></category>

		<guid isPermaLink="false">http://bhdresearch.scienceblog.com/?p=487</guid>
		<description><![CDATA[The Wellcome Trust Monitor documents the views of adults and young people in the UK about science and medical research. The survey is conducted every three years, in order to capture how public opinion is changing over time and also &#8230; <a href="http://bhdresearch.scienceblog.com/487/wellcome-trust-monitor-public-opinion-about-medical-research/">Continue reading <span class="meta-nav">&#8594;</span></a>]]></description>
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		<slash:comments>0</slash:comments>
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		<title>FLCN’s divergent DENN domain evolutionarily conserved</title>
		<link>http://bhdresearch.scienceblog.com/486/flcns-divergent-denn-domain-evolutionarily-conserved/</link>
		<comments>http://bhdresearch.scienceblog.com/486/flcns-divergent-denn-domain-evolutionarily-conserved/#comments</comments>
		<pubDate>Fri, 07 Jun 2013 08:13:06 +0000</pubDate>
		<dc:creator>bhdresearch</dc:creator>
				<category><![CDATA[Uncategorized]]></category>

		<guid isPermaLink="false">http://bhdresearch.scienceblog.com/?p=486</guid>
		<description><![CDATA[Last summer, Nookala et al., published the structure of the C-terminus of the FLCN protein, and showed that this portion of FLCN formed a divergent DENN domain. DENN domain proteins have Guanine nucleotide exchange factor (GEF) activity towards Rab GTPases, &#8230; <a href="http://bhdresearch.scienceblog.com/486/flcns-divergent-denn-domain-evolutionarily-conserved/">Continue reading <span class="meta-nav">&#8594;</span></a>]]></description>
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		<slash:comments>0</slash:comments>
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		<item>
		<title>Folliculin regulates stem cells’ exit from pluripotency</title>
		<link>http://bhdresearch.scienceblog.com/483/folliculin-regulates-stem-cells-exit-from-pluripotency/</link>
		<comments>http://bhdresearch.scienceblog.com/483/folliculin-regulates-stem-cells-exit-from-pluripotency/#comments</comments>
		<pubDate>Fri, 07 Jun 2013 08:01:37 +0000</pubDate>
		<dc:creator>bhdresearch</dc:creator>
				<category><![CDATA[Uncategorized]]></category>

		<guid isPermaLink="false">http://bhdresearch.scienceblog.com/?p=483</guid>
		<description><![CDATA[A stem cell requires two properties: self-renewal and potency. Self-renewal describes stem cell division to generate more stem cells. Potency describes stem cell division where the new cell takes on different characteristics to the progenitor cell and ultimately becomes a &#8230; <a href="http://bhdresearch.scienceblog.com/483/folliculin-regulates-stem-cells-exit-from-pluripotency/">Continue reading <span class="meta-nav">&#8594;</span></a>]]></description>
		<wfw:commentRss>http://bhdresearch.scienceblog.com/483/folliculin-regulates-stem-cells-exit-from-pluripotency/feed/</wfw:commentRss>
		<slash:comments>2</slash:comments>
		</item>
		<item>
		<title>Video Interview: Professor Vera Krymskaya &#8211; University of Pennsylvania, USA</title>
		<link>http://bhdresearch.scienceblog.com/478/video-interview-professor-vera-krymskaya-university-of-pennsylvania-usa/</link>
		<comments>http://bhdresearch.scienceblog.com/478/video-interview-professor-vera-krymskaya-university-of-pennsylvania-usa/#comments</comments>
		<pubDate>Fri, 24 May 2013 07:50:04 +0000</pubDate>
		<dc:creator>bhdresearch</dc:creator>
				<category><![CDATA[Uncategorized]]></category>

		<guid isPermaLink="false">http://bhdresearch.scienceblog.com/?p=478</guid>
		<description><![CDATA[This week we would like to introduce you to the work of Professor Vera Krymskaya, Associate Professor of Medicine at the University of Pennsylvania Perelman School of Medicine. Professor Krymskaya’s primary research interest is how signalling pathways cause disease when &#8230; <a href="http://bhdresearch.scienceblog.com/478/video-interview-professor-vera-krymskaya-university-of-pennsylvania-usa/">Continue reading <span class="meta-nav">&#8594;</span></a>]]></description>
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		<slash:comments>0</slash:comments>
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		<title>Clinical Trials – stumbling blocks and solutions</title>
		<link>http://bhdresearch.scienceblog.com/473/clinical-trials-stumbling-blocks-and-solutions/</link>
		<comments>http://bhdresearch.scienceblog.com/473/clinical-trials-stumbling-blocks-and-solutions/#comments</comments>
		<pubDate>Fri, 17 May 2013 08:00:19 +0000</pubDate>
		<dc:creator>bhdresearch</dc:creator>
				<category><![CDATA[Uncategorized]]></category>

		<guid isPermaLink="false">http://bhdresearch.scienceblog.com/?p=473</guid>
		<description><![CDATA[Scurvy was a debilitating ailment that commonly affected sailors in the 18th Century. In 1747, James Lind conducted one of the first ever clinical trials, by giving sailors with scurvy different dietary supplements and documenting the effects on their health. &#8230; <a href="http://bhdresearch.scienceblog.com/473/clinical-trials-stumbling-blocks-and-solutions/">Continue reading <span class="meta-nav">&#8594;</span></a>]]></description>
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		<title>Signalling diagram update &#8211; a review of two years&#8217; progress</title>
		<link>http://bhdresearch.scienceblog.com/471/signalling-diagram-update-a-review-of-two-years-progress/</link>
		<comments>http://bhdresearch.scienceblog.com/471/signalling-diagram-update-a-review-of-two-years-progress/#comments</comments>
		<pubDate>Fri, 10 May 2013 08:00:55 +0000</pubDate>
		<dc:creator>bhdresearch</dc:creator>
				<category><![CDATA[Uncategorized]]></category>

		<guid isPermaLink="false">http://bhdresearch.scienceblog.com/?p=471</guid>
		<description><![CDATA[The signalling diagram has been updated to include the following recent research papers: FNIP2 causes MNU-induced apoptosis (Sano et al., 2013) FLCN inhibits MMP9 (Pimenta et al., 2012) FLCN inhibits HIF-1a, mTORC1 and mTORC2 (Nishii et al., 2013) FLCN and &#8230; <a href="http://bhdresearch.scienceblog.com/471/signalling-diagram-update-a-review-of-two-years-progress/">Continue reading <span class="meta-nav">&#8594;</span></a>]]></description>
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		<slash:comments>0</slash:comments>
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		<title>Highlights and insights from the Inaugural IRDiRC Conference</title>
		<link>http://bhdresearch.scienceblog.com/468/highlights-and-insights-from-the-inaugural-irdirc-conference/</link>
		<comments>http://bhdresearch.scienceblog.com/468/highlights-and-insights-from-the-inaugural-irdirc-conference/#comments</comments>
		<pubDate>Fri, 03 May 2013 08:00:54 +0000</pubDate>
		<dc:creator>bhdresearch</dc:creator>
				<category><![CDATA[Uncategorized]]></category>

		<guid isPermaLink="false">http://bhdresearch.scienceblog.com/?p=468</guid>
		<description><![CDATA[As briefly mentioned in last week’s blog, the inaugural conference of the International Rare Disease Research Consortium (IRDiRC) was held in Dublin earlier this month. The conference brought together researchers, clinicians, policy makers and patient organisations from across the globe &#8230; <a href="http://bhdresearch.scienceblog.com/468/highlights-and-insights-from-the-inaugural-irdirc-conference/">Continue reading <span class="meta-nav">&#8594;</span></a>]]></description>
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		<slash:comments>0</slash:comments>
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		<item>
		<title>Rare disease research – new developments and initiatives</title>
		<link>http://bhdresearch.scienceblog.com/467/rare-disease-research-new-developments-and-initiatives/</link>
		<comments>http://bhdresearch.scienceblog.com/467/rare-disease-research-new-developments-and-initiatives/#comments</comments>
		<pubDate>Fri, 26 Apr 2013 07:00:32 +0000</pubDate>
		<dc:creator>bhdresearch</dc:creator>
				<category><![CDATA[Uncategorized]]></category>

		<guid isPermaLink="false">http://bhdresearch.scienceblog.com/?p=467</guid>
		<description><![CDATA[The aim of this year’s Rare Disease Day, Rare Disorders Without Borders, was to promote the message that international collaboration between patients, clinicians and researchers is imperative to find cures for rare diseases. Indeed, this has been the feeling of &#8230; <a href="http://bhdresearch.scienceblog.com/467/rare-disease-research-new-developments-and-initiatives/">Continue reading <span class="meta-nav">&#8594;</span></a>]]></description>
		<wfw:commentRss>http://bhdresearch.scienceblog.com/467/rare-disease-research-new-developments-and-initiatives/feed/</wfw:commentRss>
		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Loss of FLCN increases longevity in C. elegans</title>
		<link>http://bhdresearch.scienceblog.com/463/loss-of-flcn-increases-longevity-in-c-elegans/</link>
		<comments>http://bhdresearch.scienceblog.com/463/loss-of-flcn-increases-longevity-in-c-elegans/#comments</comments>
		<pubDate>Fri, 19 Apr 2013 11:46:46 +0000</pubDate>
		<dc:creator>bhdresearch</dc:creator>
				<category><![CDATA[Uncategorized]]></category>

		<guid isPermaLink="false">http://bhdresearch.scienceblog.com/?p=463</guid>
		<description><![CDATA[Several signalling pathways – namely the mTOR, HIF and insulin signalling pathways – are known to slow ageing and increase longevity under certain conditions. This is a topic of much research, and was discussed at the recent “Talks about TORCs” &#8230; <a href="http://bhdresearch.scienceblog.com/463/loss-of-flcn-increases-longevity-in-c-elegans/">Continue reading <span class="meta-nav">&#8594;</span></a>]]></description>
		<wfw:commentRss>http://bhdresearch.scienceblog.com/463/loss-of-flcn-increases-longevity-in-c-elegans/feed/</wfw:commentRss>
		<slash:comments>0</slash:comments>
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		<title>The Third Crick Symposium and Talks about TORCs</title>
		<link>http://bhdresearch.scienceblog.com/460/the-third-crick-symposium-and-talks-about-torcs/</link>
		<comments>http://bhdresearch.scienceblog.com/460/the-third-crick-symposium-and-talks-about-torcs/#comments</comments>
		<pubDate>Fri, 12 Apr 2013 09:00:59 +0000</pubDate>
		<dc:creator>bhdresearch</dc:creator>
				<category><![CDATA[Uncategorized]]></category>

		<guid isPermaLink="false">http://bhdresearch.scienceblog.com/?p=460</guid>
		<description><![CDATA[Last month, the Third Crick Symposium was held in London (UK), with the aim of discussing ways in which basic biological research could progress from “Genetics to molecules to therapies”. In particular, this meeting brought together chemists, biologists and clinicians &#8230; <a href="http://bhdresearch.scienceblog.com/460/the-third-crick-symposium-and-talks-about-torcs/">Continue reading <span class="meta-nav">&#8594;</span></a>]]></description>
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